Presidente do Departamento de Química
Brás, JLA, Pinheiro BA, Cameron K, Cuskin F, Viegas A, Najmudin S, Bule P, Pires VMR, Romão MJ, Bayer EA, Spencer HL, Smith S, Gilbert HJ, Alves VD, Carvalho AL, Fontes CMGA. 2016. Diverse specificity of cellulosome attachment to the bacterial cell surface, dec. SCIENTIFIC REPORTS. 6:38292.
C Coelho, A Foti, T Santos-Silva, T Hartmann, S Leimkühler and MJ Romão, Human Aldehyde Oxidase: crystal structure and inhibition studies for the understanding of xenobiotics metabolism, NATURE CHEMICAL BIOLOGY 11, 779–783 (2015) doi:10.1038/nchembio.1895
Coelho C, Mahro M, Trincão J, Carvalho AT, Ramos MJ, Terao M, Garattini E, Leimkühler S, Romão MJ. “The First Mammalian Aldehyde Oxidase Crystal Structure: Insights Into Substrate specificity.” J BIOL CHEM. 23;287(48):40690-702. doi: 10.1074/jbc.M112.390419. Epub 2012 Sep 27.
T Santos-Silva, A Mukhopadhyay, J D Seixas, G J L Bernardes, C C Romão, M J Romão “Towards Improved Therapeutic CORMs: Understanding the Reactivity of CORM-3 with Proteins” CURRENT MEDICINAL CHEMISTRY Volume: 18 Issue: 22 Pages: 3361-3366 Published: AUG 2011
Santos-Silva T, Mukhopadhyay A, Seixas JD, Bernardes, GJL, Romao, CC, Romao, MJ. “CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl-Lysozyme Complex” JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 133 Issue: 5 Pages: 1192-1195
C.Coelho, J. Trincão and M. J. Romão “The use of ionic liquids as crystallization additives allowed to overcome nanodrop scaling up problems: A success case for producing diffraction-quality crystals of a nitrate reductase” JOURNAL OF CRYSTAL GROWTH, Volume 312, Issue 5, 714-719.
Carvalho AL, Dias FM, Nagy T, Prates JA, Proctor MR, Smith N, Bayer EA, Davies GJ, Ferreira LM, Romao MJ*, Fontes CM*, Gilbert HJ. “Evidence for a dual binding mode of dockerin modules to cohesins”. PROC NATL ACAD SCI U S A. 2007 Feb 27;104(9):3089-94.
XTAL - Macromolecular Crystallography Lab