Mário Emanuel Campos de Sousa Diniz

Professor Auxiliar
Secção de Bioquímica e Biofísica
(+351) 212948386
(+351) 212948550

Interesses Científicos

Toxicologia Ambiental e Proteómica. Focado no tema da desregulação endócrina em organismos expostos a compostos desreguladores endócrinos (EDCs) no ambiente aquático. Determinação de metais pesados em águas residuais e organismos. Proteómica de organismos aquáticos e alterações climáticas. Pesquisa de novos biomarcadores em organismos expostos a poluentes. 

Publicações Representativas

C. Nuñez, J. Fernandez-Lodeiro, M. Dinis, M. Larguinho, J.L. Capelo, C. Lodeiro. (2011). Synthesis and photophysical studies of two luminescent chemosensors based on catechol and 8-Hydroxyquinoline chromophores, and their complexes with group 13 metal ions. Inorganic Chemistry Communications, Vol. 14, Issue 6, 831-835. doi:10.1016/j.inoche.2011.02.023

Elsa Mendonça, Mário Diniz, Luís Silva, Isabel Peres, Luísa Castro, José Brito Correia, Ana Picado (2011). Effects of diamond nanoparticle exposure on the internal structure and reproduction of Daphnia magna. Journal of Hazardous Materials 186 (1), 265-271 (doi:

R.J. Carreira, M.S. Diniz, J.L. Capelo (2010). New findings regarding the ultrasonic-based acceleration of protein 18O-labeling. Rapid Communications in Mass Spectrometry, 25(1), 75-87). (doi: 10.1002/rcm.4816)

Diniz, M.S., Pereira, R., Freitas, A.C., Rocha-Santos, T.A.P., Castro, L., Peres, I., Duarte, A.C. (2010). Impact of a secondary treated Bleached Kraft Pulp Mill Effluent in both sexes of gold fish (Carassius auratus L.)”. Journal of Environmental Science and Health, Part A, vol. 45(14), 1858-1865 (DOI: 10.1080/10934529.2010.520517).

Diniz, M.S., Pereira, R., Freitas, A.C., Rocha-Santos, T.A.P., Castro, L., Peres, I., Duarte, A.C. (2010). Evaluation of the Sub-lethal Toxicity of Bleached Kraft Pulp Mill Effluent to Carassius auratus and Dicentrarchus labrax. Water, Air and Soil Poll (DOI 10.1007/s11270-010-0565-z

Hugo M. Santos, Daniel Glez-Peña, Miguel Reboiro-Jato, Florentino Fdez-Riverola, Mário S. Diniz, Carlos Lodeiro, J. L. Capelo (2010). A novel 18-O inverse labeling-based workflow for accurate bottom-up mass spectrometry quantification of proteins separated by gel electrophoresis. Electrophoresis, 31(20), 3363-3507 (DOI 10.1002/elps.201000251).

Costa PM, Caeiro S, Diniz MS, Lobo J, Martins M, Ferreira AM, Caetano M, Vale C, DelValls TA, Costa MH (2010). A description of chloride cell and kidney tubule alterations in the flatfish Solea senegalensis exposed to moderately contaminated estuarine sediments. J Sea Res. 64(4), 465-472. (http://dx.doi.org/10.1016/j.seares.2010.01.005)

Diniz M.S., Maurício R., Petrovic M., de Alda L., Amaral L., Peres I., Barceló D., Santana F. (2010). Assessing the estrogenic potency in a Portuguese wastewater treatment plant using an integrated approach. J. Environ. Sci. Vol. 22, Nº 10, 1613-1622 ( http//dx.doi.org/10.1016/S1001-0742(09)60297-7).

Hugo.M. Santos, Ricardo Carreira, Mario.S. Diniz, M.G. Rivas, Carlos. Lodeiro, José J.G. Moura, José.L. Capelo (2010). Ultrasonic multiprobe as a new tool to overcome the bottleneck of throughput in workflows for protein identification relaying on ultrasonic energy. Talanta, Volume 81, Issues 1-2, 15, 55-62. http://dx.doi.org/10.1016/j.talanta.2009.11.033

T.A.P. Santos, Pereira R., L. Silva; Freitas, A.C.; Rocha-Santos, T.A.P.; Diniz, M.S.; Castro, L., Peres, I., Duarte, A.C. (2010). Effects of tertiary treatment by fungi on organic compounds in a kraft pulp mill effluent. Environmental Science and Pollution Research, Vol. 17, Nº4, 866-874 http://dx.doi.org/10.1007/s11356-009-0288-0

Reboiro-Jato, D. Glez-Peña, H.M. Santos, M.S. Diniz, C. Lodeiro, J.L. Capelo, F. Fdez-Riverola (2010). Multi-agent system for mass spectrometry analysis". Advances in Intelligent and Soft Computing series, Springer-Verlag. PAAMS 2010 proceedings, vol. 71, 87-95.

Carreira RJ, Lodeiro C, Diniz MS, Moura I, Capelo JL (2009). Can ultrasonic energy efficiently speed 18O-labeling of proteins? Proteomics, 9, 21, 4974-4977. doi: 10.1002/pmic.200900197

J.L. Capelo, R. Carreira, M. Diniz, L. Fernandes, M. Galesio, C. Lodeiro, H.M. Santos, G. Vale (2009). Overview on modern approaches to speed up protein identification workflows
Q1 relying on enzymatic cleavage and mass spectrometry-based techniques. Analytica Chimica Acta 650, 151-159 (Available on-line doi:10.1016/j.aca.2009.07.034)

Freitas, A.C., Ferreira, F., Costa, A.M., Pereira, R., Antunes, S.C., Gonçalves, F., Rocha-Santos, T.A.P., Diniz, M.S., Castro, L., Peres, I., and Duarte A.C. (2009). Biological treatment of the effluent from a bleached kraft pulp mill using basidiomycete and zygomycete fungi. Science of the Total Environment, 407, 10, 3282-3289. http://dx.doi.org/10.1016/j.scitotenv.2009.01.054

Pereira R., Antunes S.C., Gonçalves, A.M.M.; Marques S.M.; Gonçalves F.; Ferreira, F.; Freitas, A.C.; Rocha-Santos, T.A.P.; Diniz, M.S.; Castro, L., Peres, I., Duarte, A.C. (2009). The Effectiveness of a Biological Treatment with Rhyzopus oryzae and of a photo-Fenton Oxidation in the Mitigation of Toxicity of a Bleached Kraft Pulp Mill Effluent. Water Research, 43: 9, 2471-2480. http://dx.doi.org/10.1016/j.watres.2009.03.013

Costa P.M., Caeiro, S., Diniz, M.S., Lobo, J., Martins, M., Ferreira A.M., Caetano, M., Vale, C., DelValls, Á., Costa M.H. (2009). Biochemical endpoints on juvenile Solea senegalensis exposed to estuarine sediments: the role of contaminant interactions on metallothionein and CYP1A induction. Ecotoxicology, 18: 988-1000. http://dx.doi.org/10.1007/s10646-009-0373-7

Diniz, M.S., Peres, I., Castro, L., Freitas, A.C., Rocha-Santos, T.A.P., Pereira, R., Duarte, A.C. (2009). Effects of EFC-Kraft Pulp Mill Effluent Treated with Fungi (Rhyzopus oryzae) on Reproductive Steroids and Liver CYP1A of exposed Goldfish (Carassius auratus). Ecotoxicology, 18: 1011-1017. http://dx.doi.org/10.1007/s10646-009-0392-4.

Costa P.M., Diniz M.S., Caeiro S., Lobo J., Martins M., Ferreira A.M., Caetano M., Vale C.,. DelValls T.Á, Costa M.H. (2008). Histological biomarkers in gills and liver of juvenile Solea senegalensis exposed to contaminated estuarine sediments: a weighted indices approach. Aquatic Toxicology, 92 (3), 202-212. doi:10.1016/j.aquatox.2008.12.009

Costa, P.M., Santos, H.M., Peres, I., Costa, M.H., Alves, S., Capelo-Martinez, J.L., Diniz, M.S. (2008). Toxicokinetics of Waterborne Trivalent Arsenic in the Freshwater Bivalve Corbicula fluminea. Arch. Environ. Contam. Toxicol. Arch Env Contam Toxicology, 57:338-347. http://dx.doi.org/10.1007/s00244-008-9267-6

M.S. Diniz, H.M. Santos, P.M. Costa, I. Peres, M.H. Costa and J.L. Capelo (2008). Effects of exposure to arsenic in Corbicula fluminea (Muller, 1744): Evaluation of the histological, histochemical and biochemical responses. Ciencias Marinas, 34 (3) 307-316.

Mário S. Diniz, Hugo M Santos., Pedro M. Costa, Isabel Peres, Maria H. Costa, José L. Capelo (2007). Metallothionein responses in the Asiatic clam (Corbicula fluminea) after exposure to trivalent arsenic. Biomarkers, Vol. 12 (6), 589-598. DOI: 10.1080/13547500701507701

Santos, H.M, Diniz, M.S, Costa, P.M., Peres, I., Costa, M.H., Alves, S. and J.L. Capelo-Martinez (2007). Toxicological effects and bioaccumulation in the freshwater clam (Corbicula fluminea) following exposure to trivalent arsenic. Environmental Toxicology, Vol. 2 (5), 502-509. DOI: 10.1002/tox.20303

Costa, P.M., Repolho, T., Caeiro, S., Diniz, M., Duarte, A. and Costa, M.H. (2008). Modelling metallothionein induction in the liver of Sparus aurata L. 1758 exposed to metal contaminated sediments. Ecotoxicology and Environmental Safety, 71, 117-124. http://dx.doi.org/10.1016/j.ecoenv.2007.05.012

Maurício, R., Diniz, M.S. , Petrovic, M., Amaral, L., Peres I., Pihan, J.C., Barceló, D., and Santana, F. (2006). A Characterization of Selected Endocrine Disruptor Compounds in a Portuguese WasteWater Treatment Plant. Environmental Monitoring and Assessment, vol. 118, 75-87. DOI: 10.1007/s10661-006-0986-8

Diniz, M.S, Peres, I and J.C. Pihan (2005). Estrogenic effects in crucian carp (Carassius carassius) exposed to treated sewage effluent. Ecotoxicology and Environmental Safety 62, 427-435. doi:10.1016/j.ecoenv.2004.11.004

Diniz, M.S, Peres, I and J.C. Pihan (2005). Comparative estrogenic responses of mirror carp (Cyprinus carpio) exposed to a treated municipal sewage effluent (Lisbon) in two seasonal periods. The Science of Total Environment 349, 129-139. doi:10.1016/j.scitotenv.2005.01.014

Diniz, M.S, Peres, I and J.C. Pihan (2005). Crucian carp (Carassius carassius) exposure to treated waste water effluent: evidence of size influence on endocrine disruption? Rev. Biol. 23, 43-52. (PO ISSN 0034-7736).

Correia A.D., Costa F.O., Neuparth T., Diniz M.S., and M.H.Costa (2001). Sub-lethal Effects of Copper-Spiked Sediments on the Marine Amphipod Gammarus locusta: Evidence of Hormesis? Ecotoxicology and Environmental Restoration 4(2), 32-38. 


Mário Diniz - UCIBIO