Faculdade

Departamento

Maria Cristina de Oliveira Costa

Professor Auxiliar
Secção de Bioquímica e Biofísica
413
(+351) 212949663
10965
(+351) 212948550

Interesses Científicos

Isolamento e purificação de metaloproteínas.

Caracterização bioquímica e espectroscópica (UV-visível, RPE, RMN) de metaloproteínas.

Redução biológica do perclorato. 

Publicações Representativas

1. M. Santos, M.M. Correia dos Santos, M.L. Simões Gonçalves, C. Costa, J.C. Romão and J.J.G. Moura
"Redox chemistry of low-pH forms of tetrahemic cytochrome c3".
J. of Inorg. Biochemistry (2006) 100, 2009-2016.

2. G.W. Pettigrew, S.R. Pauleta, C.F. Goodhew, A. Copper, N. Margaret, J. Kornelia, H.E. Stephen, C. Costa, L. Krippahl, I. Moura and J.J.G. Moura.
"The electron transfer complexes of cytochrome c peroxidase from Paracoccus denitrificans containing more than one cytochrome".
Biochemistry (2003) 42, 11968-11981.

3. C. Cunha, S. Macieira, J.M.Dias, M.G. Almeida, L.L.Gonçalves, C. Costa, J. Lampreia, R. Huber, J.J.G. Moura, I. Moura and M.J. Romão.
"Cytochrome c nitrite Reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA)".
J.Biol. Chem. (2003) 278, 17455-17465.

4. M.G. Almeida, S. Macieira, L.L.Gonçalves, R. Huber, C. Cunha, M.J. Romão, C. Costa, J. Lampreia, J.J.G. Moura and I. Moura.
"The Isolation and Characterization of Cytochrome c Nitrite Reductase Subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774. Re-evaluation of the spectroscopic data and redox properties".
Eur.J.Biochem. (2003) 270, 3904-3915.

5. G.N.George, C.Costa, J.J.G.Moura and I.Moura.
"Observation of ligand-based redox chemistry at the active site of a molybdenum enzyme".
JACS (1999) 121, 22621-26626.
Biological reduction of perchlorate.
Isolation, purification and characterization of metalloproteins, with