Faculdade

Departamento

Filipa Margarida Barradas de Morais Marcelo

Assistant Researcher
Secção de Química
303
(+351) 212948300
11401
(+351) 212948550

Research Interests

Carbohydrate-Protein Molecular Recognition using NMR techniques and Modelling Methods.

Main Publications

Stereochemical Assignment and First Synthesis of the Core of Miharamycin Antibiotics, F. Marcelo, J. Jiménez-Barbero, J. Marrot, A. P. Rauter, P. Sinaÿ, Y. Blériot, Chemistry Eur. J. 2008, 14, 10066 – 10073.

Molecular Basis for Inhibition of GH84 Glycoside Hydrolases by Substituted Azepanes; Conformational Flexibility Enables Probing of Substrate Distortion, F. Marcelo, Y. He, S. A. Yuzwa, L. Nieto, J. Jiménez-Barbero, M. Sollogoub, D. J. Vocadlo, G. D. Davies, Y. Blériot J. Am. Chem. Soc. 2009, 131, 5390-5392.

Carbohydrate Recognition at the Minor-Groove of the Self-Complementary Duplex d(CGCGAATTCGCG) 2 by a Synthetic Glyco-oligoamide, P. Peñalver, F. Marcelo, J. Jiménez-Barbero, C. Vicent, Chem. Eur. J. 2011, 17, 4561-4570.

Engineering O-glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-associated Glycopeptides, F. Corzana, J. H. Busto, F. Marcelo, M. G. Luis, J. L. Asensio, S. Martín-Santamaría, J. Jiménez-Barbero, A. Avenoza, J. M. Peregrina, Chem. Eur. J. 2011, 17, 3105-3110.