Carlos Lodeiro Y Espiño

Full Professor
Chemistry Section
(+351) 212948300

Áreas de Investigação

Metallic and soft Nanoparticles, Metal Complexes, Proteomics, Fluorescent sensors, Colourimetric systems, Nanomaterials and Polymeric composites.

Research Interests

Fluorescence dyes and materials for recognition, detection, quantification, drug delivery and imaging. 

Organic and Inorganic Synthesis of new fluorescence dyes, chemosensors and metal complexes.

Functionalized Nanomaterials: Nanoparticles, polymers and composites, and Metallomesogens – Fluorescent Liquid Crystals.

Nanotechnology for biomedicine, nano-proteomics and environmental hazard control: Synthesis and functionalization of metal complexes, nanoparticles and composites (Au, Ag, Pt, Pd; SiO2, Fe2O3, Au@/Ag@SiO2, Au@ Fe2O3, and CuO2, Polymers, MSiNP, Se/Te Nanocomposites). QDs and SiQDs, Metallic and Soft nanomaterials.

Developments and validation of analytical and structural analytical techniques: UV-vis and Fluorescence Spectroscopy, Transmission Electron Microscopy, Dynamic Light Scattering, HPLC and nano-LC, Supramolecular Separations, 1D and 2D-Gel Electrophoresis, Mass Spectrometry (MALDI and ESI applications).

Biomarker discovery using MS/MS techniques applied in Cancer Research and Aging Diseases applying nanoparticles. New fast methodologies for sample preparation and biomarker detection using MALDI TOF and ESI TOF MS-MS techniques are applied in biological samples, urine, serum, blood, synovial liquid, peritoneal liquid, etc. Applications of Liquid Biopsia approach into fast diagnosis.

Development and Applications of Metal nanoparticles for Proteomics research.

Main Publications

13.-Tuning and reviving the luminescence of a new class of pyridyl β-diketonate Eu(III) metallomesogens: From molecules to entrapment in polymer particles. Brais González, Frederico Duarte, Carlos Fernández-Lodeiro, Javier Fernández-Lodeiro, Mercedes Cano, Carlos Lodeiro, Cristián Cuerva, Dyes and Pigments, Volume 204August 2022 Article number 110440. https://doi.org/10.1016/j.dyepig.2022.110440


12.-Functional Cyanine-Based PVA: PVP Polymers as Antimicrobial Tools toward Food and Health-Care Bacterial Infections. Gonçalo Marcelo, Joana Galhano, Maria Paula Duarte, Atanas Kurutos, José Luis Capelo-Martinez, Carlos Lodeiro, Elisabete Oliveira. Macromolecular Bioscience, Volume 22, Issue 1 2. December 2022 Article number 2200244. https://doi.org/10.1002/mabi.202200244


11.- Polyallylamine assisted synthesis of 3D branched AuNPs with plasmon tunability in the vis-NIR region as refractive index sensitivity probes.  Silvia Nuti, Carlos Fernandez Lodeiro, Javier Fernandez Lodeiro, Adrian Fernandez Lodeiro, Jorge Perez Juste, Isabel Pastoriza Santos, Alec Lagrow, Oscar Schraidt, Jose Luis Capelo-Martinez, Carlos Lodeiro. J. Colloid & Interf. Sci. 611, 695-705  (2021). DOI: https://doi.org/10.1016/j.jcis.2021.12.047


10.-  Advanced functional luminescent metallomesogens: the key role of the metal centre. Cristian Cuerva, Mercedes Cano, Carlos Lodeiro. Chemical Reviews (ACS) 121, 20, 12966-13010 (2021). DOI: https://doi.org/10.1021/acs.chemrev.1c00011


9.-  Absolute quantitative proteomics using the total protein approach to identify novel clinical immunohistochemical markers in renal neoplasms. Susana Jorge; José L. Capelo; William LaFramboise; Swati Satturwar; Dimitrios Korentzelos; Sheldon Bastacky; Gabriela Quiroga-Garza; Rajiv Dhir; Jacek R. Wisniewski; Carlos Lodeiro; Hugo Miguel Santos. BCM Medicine (2021) (Springer-Nature). DOI: https://doi.org/10.1186/s12916-021-02071-9


8.- Water Soluble hollow nanocrystals from self-assembly of AIEE-active Pt(II) metallomesogens. Cristian Cuerva, Javier Fernandez-Lodeiro, Mercedes Cano, Jose Luis Capelo-Martinez, Carlos Lodeiro. NanoResearch 14(1),  245-254 (2021). DOI: https://doi.org/10.1007/s12274-020-3078-0


7.-  The versatility of Fe(II) in the synthesis of uniform citrate-stabilized plasmonic nanoparticles with tunable size at room temperature. Carlos Fernández-Lodeiro, Javier Fernández-Lodeiro,  Enrique Carbó-Argibay, Carlos Lodeiro,  Jorge Pérez-Juste and Isabel Pastoriza-Santos. Nano research (2020)  13, 2351–2355(2020). DOI: https://doi.org/10.1007/s12274-020-2854-1


6.-  Magnetic, fluorescent and hybrid nanoparticles: From synthesis to application in biosystems. Gonçalo A. Marcelo, Carlos Lodeiro, Jose Luis Capelo, Julia Lorenzo, Elisabete Oliveira. Materials Science and Engineering C, (2020), 106, 110104. DOI: https://doi.org/10.1016/j.msec.2019.110104


5.- Ultrasonically assisted extraction and digestion of proteins from solid biopsies followed by peptide sequential extraction hyphenated to MALDI-based profiling hold the promise of distinguishing renal oncocytoma from chromophobe renal cell carcinoma. Susana Jorge; Kevin Pereira; Hugo López-Fernández; William LaFramboise; Rajiv Dhir; Javier Fernández-Lodeiro; Carlos Lodeiro; Hugo M Santos.  Talanta  (2020), 206, 120180.  DOI: https://doi.org/10.1016/j.talanta.2019.120180


4.-  Susana Jorge, Eduardo Araujo; Antonella Chiechi, Hugo M. Santos, Anna Galstayan, Julia Lyudbimova,  Jose Luis Capelo Martinez,  Carlos Lodeiro, Mario Diniz, M. T. Klein. Proteomic changes driven by urban pollution suggest particulate matter as a deregulator of energy metabolism, mitochondrial activity, and oxidative pathways in the rat brain. Science of the Total Environment  (2019), 687, pp. 839-848. DOI: https://doi.org/10.1016/j.scitotenv.2019.06.102


3.-  Iron(II) as a Green Reducing Agent in Gold Nanoparticle Synthesis. Jamila Djafari, Adrian Fernandez-Lodeiro, Daniel Garcia Lojo, Benito Rodriguez Gonzalez, Jose Luis Capelo, Isabel Pastoriza, Jorge Perez Juste, Carlos Lodeiro, Javier Fernandez Lodeiro.ACS Sustainable Chemistry & Engineering, (ASC) (2019), 7 (9), pp 8295–8302. DOI: https://doi.org10.1021/acssuschemeng.8b06690


2.-  Highly accessible aqueous synthesis of well-dispersed dendrimer-type platinum nanoparticles and their catalytic applications.Adrian Fernandez-Lodeiro, Jamila Djafari, David Lopez Tejedor, Carlos Perez Rizquez, Benito Rodriguez Gonzalez, Jose Luis Capelo, Jose M.Palomo, Carlos Lodeiro, Javier Fernandez Lodeiro. Nano Research (Springer) (2019) May 2019, 12, 5, 1083-1093. DOI: https://doi.org/10.10007/s12274-019-2350-7


1.-  Martins, G.; Fernández-Lodeiro, J.; Djafari, J.; Lodeiro, C.; Capelo, J.L.; Santos, H. M.. Label-free protein quantification after ultrafast digestion of complex proteomes using ultrasonic energy and immobilized-trypsin magnetic nanoparticles. Talanta (2019), 196, 262-270. DOI: https://doi.org/10.1016/j.talanta.2018.12.066 




Carlos Lodeiro @LAQV

ORCID [0000-0001-5582-5446]

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