Ricardo Jorge Flores Branco

Invited Researcher
Secção de Engenharia Química e Bioquímica
(+351) 212948300
(+351) 212948550

Research Interests

Theoretical and Computational Chemistry
Molecular Modeling of Metalloproteins
Molecular Dynamics Simulation of Biological Systems
Enzyme Catalytic Mechanisms and Solvent Networks
Selective Biocatalyst Rational Design
Protein Structure-Function Relationships
Molecular Evolution
Structural Bioinformatics 

Main Publications

1. Branco, R. J. F.; Graber, M.; Denis, V.; Pleiss, J., Molecular Mechanism of the Hydration of Candida antarctica Lipase B in the Gas Phase: Water Adsorption Isotherms and Molecular Dynamics Simulations, ChemBioChem, 2009, 10, 1-8.

2. Branco, R. J. F.; Seifert, A.; Budde, M.; Urlacher, V. B.; Ramos, M. J.; Pleiss, J., Anchoring Effects in a Wide Binding Pocket: The Molecular Basis of Regioselectivity in Engineered Cytochrome P450 Monooxygenase from B. megaterium, Proteins 2008, 73 (3), 597-607.

3. Branco, R. J. F.; Fernandes, P. A.; Ramos, M. J., Cu, Zn Superoxide dismutase: distorted active site binds substrate without significant energetic cost. Theoretical Chemistry Accounts 2006, 115 (1), 27-31.

4. Branco, R. J. F.; Fernandes, P. A.; Ramos, M. J., Molecular dynamic simulation of the Cu, Zn Superoxide Dismutase. Journal of Physical Chemistry B 2006, 110, 16754-16762.

5. Branco, R. J. F.; Fernandes, P. A.; Ramos, M. J., Density-functional calculations of the Cu, Zn superoxide dismutase redox potential: The influence of active site distortion. Theochem-Journal of Molecular Structure 2005, 729, 151-156.