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WHAT'S UP DOC?
Ask the HPLC Troubleshooter
TELL ME WHAT YOUR TROUBLES ARE
SYMPTOMS, DISEASES, AND MEDICINES
Point where it hurts to
No peaks
Very small peaks
No flow
Lower pressure
Higher pressure
Variable retention
Change on separation
Splitted peaks
Tailing
Fronting
Rounded peaks
Base line drift
Base line noise
Broad peaks
Change in peak height
Negative peaks
Ghost peaks
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