Raquel Eliana Lourenço Grazina

Investigador Pós-Doc
Secção de Bioquímica e Biofísica

Gabinete: 410C
Laboratório: 410

Telefone Departamental: (+351) 212948300 Extensão: 10948
Fax: (+351) 212948550
Email: raquel.grazina@fct.unl.pt

Interesses Científicos

- Isolation and characterization of metalloproteins containing iron-sulfur centers such as ferredoxins, using specific techniques: NMR, EPR, Mössbauer and also electrochemical studies. Molecular biology research related with protein overexpression and design of single mutants.
- Development of new poli-hydroxypyridinonate molecular systems with potential application in clinical and environmental uses. Synthesis, interaction with metal ions and biological studies.

Publicações Representativas

“A new immobilized hydroxypyridinone as a sequestering agent for heavy metal ions”. M. Amélia Santos, Raquel Grazina. J. Phys. IV, 107, 1185-1188, 2003.

"A new bipodal carboxy-bis(hydroxypiridinonate) ligand. Synthesis and complexation with copper(II), nickel(II) and zinc(II) in aqueous solution”. M. Amélia Santos, Raquel Grazina, Péter Buglyó, Sofia Gama, Etelka Farkas. Polyhedron, 21, 2609-2616, 2002.

“Transition Metal Ion Complexes of Two New Amino-Dihydroxamic Acids”. M. Amélia Santos, Raquel Grazina, Margarida Pinto, Etelka Farkas. Inorganica Chimica Acta, 321, 42-48, 2001.

“Synthesis, chelating properties towards gallium and biological evaluation of two N-substitued 3- hydroxy-4-pyridinones”. M. A. Santos, R. Grazina, A. Q. Neto, G. Cantinho, L.Gano, L. Patricio, J. of Inorg. Biochem., 78, 303-311, 2000.

“Siderophore Analogues. A new Macrociclic tetraminetrishydroxamate Ligand. Synthesis and Solution Chemistry of the Iron (III), Aluminium (III) and Copper (II) Complexes” . Margarida Gaspar, Raquel Grazina, Andrea Bodor, Etelka Farkas, M. Amélia Santos, J. Chem. Soc. Dalton Trans., 799-806, 1999.